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G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells

The G-protein-coupled estrogen receptor (GPER) mediates rapid non-genomic effects of estrogen. Although GPER is able to induce proliferation, it is down-regulated in breast, ovarian and colorectal cancer. During cancer progression, high expression levels of GPER are favorable for patients’ survival....

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Detalles Bibliográficos
Autores principales: Vo, Diep-Khanh Ho, Hartig, Roland, Weinert, Sönke, Haybaeck, Johannes, Nass, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769846/
https://www.ncbi.nlm.nih.gov/pubmed/31540491
http://dx.doi.org/10.3390/biom9090503