Melatonin Enhances Mitophagy by Upregulating Expression of Heat Shock 70 kDa Protein 1L in Human Mesenchymal Stem Cells under Oxidative Stress

Human mesenchymal stem cells (hMSCs) are a potent source of cell-based regenerative therapeutics used to treat patients with ischemic disease. However, disease-induced oxidative stress disrupts mitochondrial homeostasis in transplanted hMSCs, resulting in hMSC apoptosis and reducing their efficacy p...

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Detalles Bibliográficos
Autores principales: Yoon, Yeo Min, Kim, Hyung Joo, Lee, Jun Hee, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769944/
https://www.ncbi.nlm.nih.gov/pubmed/31540288
http://dx.doi.org/10.3390/ijms20184545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769944/
https://www.ncbi.nlm.nih.gov/pubmed/31540288
http://dx.doi.org/10.3390/ijms20184545

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