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Melatonin Enhances Mitophagy by Upregulating Expression of Heat Shock 70 kDa Protein 1L in Human Mesenchymal Stem Cells under Oxidative Stress

Human mesenchymal stem cells (hMSCs) are a potent source of cell-based regenerative therapeutics used to treat patients with ischemic disease. However, disease-induced oxidative stress disrupts mitochondrial homeostasis in transplanted hMSCs, resulting in hMSC apoptosis and reducing their efficacy p...

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Detalles Bibliográficos
Autores principales:	Yoon, Yeo Min, Kim, Hyung Joo, Lee, Jun Hee, Lee, Sang Hun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769944/ https://www.ncbi.nlm.nih.gov/pubmed/31540288 http://dx.doi.org/10.3390/ijms20184545

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