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Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia
Obesity is associated with metabolic endotoxemia, reactive oxygen species (ROS), chronic inflammation, and obese kidney fibrosis. Although the fat–intestine–kidney axis has been documented, the pathomechanism and therapeutic targets of obese kidney fibrosis remain unelucidated. To mimic obese humans...
Autores principales: | Chang, Jia-Feng, Yeh, Jih-Chen, Ho, Chun-Ta, Liu, Shih-Hao, Hsieh, Chih-Yu, Wang, Ting-Ming, Chang, Shu-Wei, Lee, I-Ta, Huang, Kuo-Yang, Wang, Jen-Yu, Lin, Wei-Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769974/ https://www.ncbi.nlm.nih.gov/pubmed/31500176 http://dx.doi.org/10.3390/ijms20184393 |
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