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New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease

Non-alcoholic steatohepatitis (NASH) is a major cause of chronic liver disease. However, most available animal models fail to reflect the whole spectrum of the disease. Liver fibrosis and portal hypertension are the strongest prognostic markers in advanced NASH. We herein aimed at developing a new m...

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Detalles Bibliográficos
Autores principales: Maeso-Díaz, Raquel, Boyer-Diaz, Zoe, Lozano, Juan José, Ortega-Ribera, Martí, Peralta, Carmen, Bosch, Jaime, Gracia-Sancho, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770035/
https://www.ncbi.nlm.nih.gov/pubmed/31510105
http://dx.doi.org/10.3390/cells8091062

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