Cyclosporin A Increases Mitochondrial Buffering of Calcium: An Additional Mechanism in Delaying Mitochondrial Permeability Transition Pore Opening

Regulation of mitochondrial free Ca(2+) is critically important for cellular homeostasis. An increase in mitochondrial matrix free Ca(2+) concentration ([Ca(2+)](m)) predisposes mitochondria to opening of the permeability transition pore (mPTP). Opening of the pore can be delayed by cyclosporin A (C...

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Detalles Bibliográficos
Autores principales: Mishra, Jyotsna, Davani, Ariea J., Natarajan, Gayathri K., Kwok, Wai-Meng, Stowe, David F., Camara, Amadou K.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770067/
https://www.ncbi.nlm.nih.gov/pubmed/31500337
http://dx.doi.org/10.3390/cells8091052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770067/
https://www.ncbi.nlm.nih.gov/pubmed/31500337
http://dx.doi.org/10.3390/cells8091052

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