XIAP as a Target of New Small Organic Natural Molecules Inducing Human Cancer Cell Death

X-linked inhibitor of apoptosis protein (XIAP) is an emerging crucial therapeutic target in cancer. We report on the discovery and characterisation of small organic molecules from Piper genus plants exhibiting XIAP antagonism, namely erioquinol, a quinol substituted in the 4-position with an alkenyl...

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Detalles Bibliográficos
Autores principales: Muñoz, Diego, Brucoli, Martina, Zecchini, Silvia, Sandoval-Hernandez, Adrian, Arboleda, Gonzalo, Lopez-Vallejo, Fabian, Delgado, Wilman, Giovarelli, Matteo, Coazzoli, Marco, Catalani, Elisabetta, Palma, Clara De, Perrotta, Cristiana, Cuca, Luis, Clementi, Emilio, Cervia, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770071/
https://www.ncbi.nlm.nih.gov/pubmed/31505859
http://dx.doi.org/10.3390/cancers11091336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770071/
https://www.ncbi.nlm.nih.gov/pubmed/31505859
http://dx.doi.org/10.3390/cancers11091336

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