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XIAP as a Target of New Small Organic Natural Molecules Inducing Human Cancer Cell Death
X-linked inhibitor of apoptosis protein (XIAP) is an emerging crucial therapeutic target in cancer. We report on the discovery and characterisation of small organic molecules from Piper genus plants exhibiting XIAP antagonism, namely erioquinol, a quinol substituted in the 4-position with an alkenyl...
Autores principales: | Muñoz, Diego, Brucoli, Martina, Zecchini, Silvia, Sandoval-Hernandez, Adrian, Arboleda, Gonzalo, Lopez-Vallejo, Fabian, Delgado, Wilman, Giovarelli, Matteo, Coazzoli, Marco, Catalani, Elisabetta, Palma, Clara De, Perrotta, Cristiana, Cuca, Luis, Clementi, Emilio, Cervia, Davide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770071/ https://www.ncbi.nlm.nih.gov/pubmed/31505859 http://dx.doi.org/10.3390/cancers11091336 |
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