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Effect of Adenomatous Polyposis Coli Loss on Tumorigenic Potential in Pancreatic Ductal Adenocarcinoma

Loss of the Adenomatous Polyposis Coli (APC) tumor suppressor in colorectal cancer elicits rapid signaling through the Wnt/β-catenin signaling pathway. In contrast to this well-established role of APC, recent studies from our laboratory demonstrated that APC functions through Wnt-independent pathway...

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Detalles Bibliográficos
Autores principales:	Cole, Jennifer M., Simmons, Kaitlyn, Prosperi, Jenifer R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770120/ https://www.ncbi.nlm.nih.gov/pubmed/31540078 http://dx.doi.org/10.3390/cells8091084

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