ProTAME Arrest in Mammalian Oocytes and Embryos Does Not Require Spindle Assembly Checkpoint Activity

In both mitosis and meiosis, metaphase to anaphase transition requires the activity of a ubiquitin ligase known as anaphase promoting complex/cyclosome (APC/C). The activation of APC/C in metaphase is under the control of the checkpoint mechanism, called the spindle assembly checkpoint (SAC), which...

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Detalles Bibliográficos
Autores principales: Radonova, Lenka, Svobodova, Tereza, Skultety, Michal, Mrkva, Ondrej, Libichova, Lenka, Stein, Paula, Anger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770151/
https://www.ncbi.nlm.nih.gov/pubmed/31540287
http://dx.doi.org/10.3390/ijms20184537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770151/
https://www.ncbi.nlm.nih.gov/pubmed/31540287
http://dx.doi.org/10.3390/ijms20184537

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