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ProTAME Arrest in Mammalian Oocytes and Embryos Does Not Require Spindle Assembly Checkpoint Activity

In both mitosis and meiosis, metaphase to anaphase transition requires the activity of a ubiquitin ligase known as anaphase promoting complex/cyclosome (APC/C). The activation of APC/C in metaphase is under the control of the checkpoint mechanism, called the spindle assembly checkpoint (SAC), which...

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Detalles Bibliográficos
Autores principales:	Radonova, Lenka, Svobodova, Tereza, Skultety, Michal, Mrkva, Ondrej, Libichova, Lenka, Stein, Paula, Anger, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770151/ https://www.ncbi.nlm.nih.gov/pubmed/31540287 http://dx.doi.org/10.3390/ijms20184537

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