Affinity Purification of NF1 Protein–Protein Interactors Identifies Keratins and Neurofibromin Itself as Binding Partners

Neurofibromatosis Type 1 (NF1) is caused by pathogenic variants in the NF1 gene encoding neurofibromin. Definition of NF1 protein–protein interactions (PPIs) has been difficult and lacks replication, making it challenging to define binding partners that modulate its function. We created a novel tand...

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Detalles Bibliográficos
Autores principales: Carnes, Rachel M., Kesterson, Robert A., Korf, Bruce R., Mobley, James A., Wallis, Deeann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770187/
https://www.ncbi.nlm.nih.gov/pubmed/31466283
http://dx.doi.org/10.3390/genes10090650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770187/
https://www.ncbi.nlm.nih.gov/pubmed/31466283
http://dx.doi.org/10.3390/genes10090650

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