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Empagliflozin Protects HK-2 Cells from High Glucose-Mediated Injuries via a Mitochondrial Mechanism

Empagliflozin is known to retard the progression of kidney disease in diabetic patients. However, the underlying mechanism is incompletely understood. High glucose induces oxidative stress in renal tubules, eventually leading to mitochondrial damage. Here, we investigated whether empagliflozin exhib...

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Detalles Bibliográficos
Autores principales: Lee, Wen-Chin, Chau, You-Ying, Ng, Hwee-Yeong, Chen, Chiu-Hua, Wang, Pei-Wen, Liou, Chia-Wei, Lin, Tsu-Kung, Chen, Jin-Bor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770192/
https://www.ncbi.nlm.nih.gov/pubmed/31540085
http://dx.doi.org/10.3390/cells8091085