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Regulation of Ketogenic Enzyme HMGCS2 by Wnt/β-catenin/PPARγ Pathway in Intestinal Cells

The Wnt/β-catenin pathway plays a crucial role in development and renewal of the intestinal epithelium. Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2), a rate-limiting ketogenic enzyme in the synthesis of ketone body β-hydroxybutyrate (βHB), contributes to the regulation of intesti...

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Detalles Bibliográficos
Autores principales:	Kim, Ji Tae, Li, Chang, Weiss, Heidi L., Zhou, Yuning, Liu, Chunming, Wang, Qingding, Evers, B. Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770209/ https://www.ncbi.nlm.nih.gov/pubmed/31546785 http://dx.doi.org/10.3390/cells8091106

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