Cargando…
Disruption of the NF-κB/IL-8 Signaling Axis by Sulconazole Inhibits Human Breast Cancer Stem Cell Formation
Breast cancer stem cells (BCSCs) are tumor-initiating cells that possess the capacity for self-renewal. Cancer stem cells (CSCs) are responsible for poor outcomes caused by therapeutic resistance. In our study, we found that sulconazole—an antifungal medicine in the imidazole class—inhibited cell pr...
Autores principales: | Choi, Hack Sun, Kim, Ji-Hyang, Kim, Su-Lim, Lee, Dong-Sun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770215/ https://www.ncbi.nlm.nih.gov/pubmed/31480284 http://dx.doi.org/10.3390/cells8091007 |
Ejemplares similares
-
Structural confirmation of sulconazole sulfoxide as the primary degradation product of sulconazole nitrate
por: Xu, Qun, et al.
Publicado: (2018) -
The PAK1-Stat3 Signaling Pathway Activates IL-6 Gene Transcription and Human Breast Cancer Stem Cell Formation
por: Kim, Ji-Hyang, et al.
Publicado: (2019) -
6-Methoxymellein Isolated from Carrot (Daucus carota L.) Targets Breast Cancer Stem Cells by Regulating NF-κB Signaling
por: Liu, Ren, et al.
Publicado: (2020) -
Machilin D, a Lignin Derived from Saururus chinensis, Suppresses Breast Cancer Stem Cells and Inhibits NF-κB Signaling
por: Zhen, Xing, et al.
Publicado: (2020) -
Development of sulconazole-loaded nanoemulsions for enhancement of transdermal permeation and antifungal activity
por: Yang, Qing, et al.
Publicado: (2019)