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Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research

Our poor understanding of the intricate biology of cancer and the limited availability of preclinical models that faithfully recapitulate the complexity of tumors are primary contributors to the high failure rate of novel therapeutics in oncology clinical studies. To address this need, patient-deriv...

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Detalles Bibliográficos
Autores principales: Inoue, Akira, Deem, Angela K., Kopetz, Scott, Heffernan, Timothy P., Draetta, Giulio F., Carugo, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770280/
https://www.ncbi.nlm.nih.gov/pubmed/31500168
http://dx.doi.org/10.3390/cancers11091321