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Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research
Our poor understanding of the intricate biology of cancer and the limited availability of preclinical models that faithfully recapitulate the complexity of tumors are primary contributors to the high failure rate of novel therapeutics in oncology clinical studies. To address this need, patient-deriv...
Autores principales: | Inoue, Akira, Deem, Angela K., Kopetz, Scott, Heffernan, Timothy P., Draetta, Giulio F., Carugo, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770280/ https://www.ncbi.nlm.nih.gov/pubmed/31500168 http://dx.doi.org/10.3390/cancers11091321 |
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