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Molecular Modeling Studies on the Binding Mode of the PD-1/PD-L1 Complex Inhibitors
The programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) is an immune checkpoint (ICP) overexpressed in various types of tumors; thus, it has been considered as an important target for cancer therapy. To determine important residues for ligand binding, we applied molecular d...
Autores principales: | Almahmoud, Suliman, Zhong, Haizhen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770281/ https://www.ncbi.nlm.nih.gov/pubmed/31546905 http://dx.doi.org/10.3390/ijms20184654 |
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