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A Review of Potential Beneficial Effects of Honey on Bone Health
Bone remodelling is a complex and tightly regulated process. Disruption of bone remodelling skewing towards resorption will cause osteoporosis and increase the risk of fragility fracture. Honey is a natural product containing various bioactive ingredients with health benefits, especially polyphenols...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770370/ https://www.ncbi.nlm.nih.gov/pubmed/31641368 http://dx.doi.org/10.1155/2019/8543618 |
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author | Kamaruzzaman, Mohd Amir Chin, Kok-Yong Mohd Ramli, Elvy Suhana |
author_facet | Kamaruzzaman, Mohd Amir Chin, Kok-Yong Mohd Ramli, Elvy Suhana |
author_sort | Kamaruzzaman, Mohd Amir |
collection | PubMed |
description | Bone remodelling is a complex and tightly regulated process. Disruption of bone remodelling skewing towards resorption will cause osteoporosis and increase the risk of fragility fracture. Honey is a natural product containing various bioactive ingredients with health benefits, especially polyphenols. Therefore, honey may be a novel dietary supplement to prevent osteoporosis. This review aims to summarize the current evidence on the effects of honey on bone health. The evidence reported so far indicates a skeletal-beneficial effect of honey in animal models of osteoporosis. However, the number of studies on humans is limited. Honey can protect the bone via its antioxidant and anti-inflammatory properties, primarily through its polyphenol content that acts upon several signalling pathways, leading to bone anabolic and antiresorptive effects. In conclusion, honey is a potential functional food for bone health, but the dose and the bioactive contents of honey need to be verified prior to its application in humans. |
format | Online Article Text |
id | pubmed-6770370 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-67703702019-10-22 A Review of Potential Beneficial Effects of Honey on Bone Health Kamaruzzaman, Mohd Amir Chin, Kok-Yong Mohd Ramli, Elvy Suhana Evid Based Complement Alternat Med Review Article Bone remodelling is a complex and tightly regulated process. Disruption of bone remodelling skewing towards resorption will cause osteoporosis and increase the risk of fragility fracture. Honey is a natural product containing various bioactive ingredients with health benefits, especially polyphenols. Therefore, honey may be a novel dietary supplement to prevent osteoporosis. This review aims to summarize the current evidence on the effects of honey on bone health. The evidence reported so far indicates a skeletal-beneficial effect of honey in animal models of osteoporosis. However, the number of studies on humans is limited. Honey can protect the bone via its antioxidant and anti-inflammatory properties, primarily through its polyphenol content that acts upon several signalling pathways, leading to bone anabolic and antiresorptive effects. In conclusion, honey is a potential functional food for bone health, but the dose and the bioactive contents of honey need to be verified prior to its application in humans. Hindawi 2019-09-19 /pmc/articles/PMC6770370/ /pubmed/31641368 http://dx.doi.org/10.1155/2019/8543618 Text en Copyright © 2019 Mohd Amir Kamaruzzaman et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Kamaruzzaman, Mohd Amir Chin, Kok-Yong Mohd Ramli, Elvy Suhana A Review of Potential Beneficial Effects of Honey on Bone Health |
title | A Review of Potential Beneficial Effects of Honey on Bone Health |
title_full | A Review of Potential Beneficial Effects of Honey on Bone Health |
title_fullStr | A Review of Potential Beneficial Effects of Honey on Bone Health |
title_full_unstemmed | A Review of Potential Beneficial Effects of Honey on Bone Health |
title_short | A Review of Potential Beneficial Effects of Honey on Bone Health |
title_sort | review of potential beneficial effects of honey on bone health |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770370/ https://www.ncbi.nlm.nih.gov/pubmed/31641368 http://dx.doi.org/10.1155/2019/8543618 |
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