Maternal Haplotypes in DHFR Promoter and MTHFR Gene in Tuning Childhood Acute Lymphoblastic Leukemia Onset-Latency: Genetic/Epigenetic Mother/Child Dyad Study (GEMCDS)

Childhood acute lymphoblastic leukemia (ALL) peaks around age 2–4, and in utero genetic epigenetic mother-fetus crosstalk might tune ALL onset during childhood life. Folate genes variably interact with vitamin status on ALL risk and prognosis. We investigated DHFR and MTHFR gene variants in 235 ALL...

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Detalles Bibliográficos
Autores principales: Tisato, Veronica, Muggeo, Paola, Lupiano, Tracy, Longo, Giovanna, Serino, Maria Luisa, Grassi, Massimo, Arcamone, Ermanno, Secchiero, Paola, Zauli, Giorgio, Santoro, Nicola, Gemmati, Donato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770441/
https://www.ncbi.nlm.nih.gov/pubmed/31443485
http://dx.doi.org/10.3390/genes10090634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770441/
https://www.ncbi.nlm.nih.gov/pubmed/31443485
http://dx.doi.org/10.3390/genes10090634

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