Severity of Dyskinesia and D3R Signaling Changes Induced by L-DOPA Treatment of Hemiparkinsonian Rats Are Features Inherent to the Treated Subjects

Extensive damage to nigrostriatal dopaminergic neurons leads to Parkinson’s disease (PD). To date, the most effective treatment has been administration of levodopa (L-DOPA) to increase dopaminergic tone. This treatment leads to responses that vary widely among patients, from predominantly beneficial...

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Detalles Bibliográficos
Autores principales: Albarrán-Bravo, Sacnité, Ávalos-Fuentes, José Arturo, Cortés, Hernán, Rodriguez-Sánchez, Marina, Leyva-García, Norberto, Rangel-Barajas, Claudia, Erlij, David, Florán, Benjamín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770442/
https://www.ncbi.nlm.nih.gov/pubmed/31480516
http://dx.doi.org/10.3390/biom9090431

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