Expression of Oncogenic Drivers in 3D Cell Culture Depends on Nuclear ATP Synthesis by NUDT5

The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer progression, as well as for early drug discovery and validation. We have previously described a novel pathway in breast cancer cells, whereby ADP (Adenosine diphosphate)-...

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Detalles Bibliográficos
Autores principales: Pickup, Katherine E., Pardow, Felicitas, Carbonell-Caballero, José, Lioutas, Antonios, Villanueva-Cañas, José Luis, Wright, Roni H. G., Beato, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770457/
https://www.ncbi.nlm.nih.gov/pubmed/31510016
http://dx.doi.org/10.3390/cancers11091337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770457/
https://www.ncbi.nlm.nih.gov/pubmed/31510016
http://dx.doi.org/10.3390/cancers11091337

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