Cargando…
Expression of Oncogenic Drivers in 3D Cell Culture Depends on Nuclear ATP Synthesis by NUDT5
The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer progression, as well as for early drug discovery and validation. We have previously described a novel pathway in breast cancer cells, whereby ADP (Adenosine diphosphate)-...
Autores principales: | Pickup, Katherine E., Pardow, Felicitas, Carbonell-Caballero, José, Lioutas, Antonios, Villanueva-Cañas, José Luis, Wright, Roni H. G., Beato, Miguel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770457/ https://www.ncbi.nlm.nih.gov/pubmed/31510016 http://dx.doi.org/10.3390/cancers11091337 |
Ejemplares similares
-
Role of the NUDT Enzymes in Breast Cancer
por: Wright, Roni H. G., et al.
Publicado: (2021) -
Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone
por: Wright, Roni H. G., et al.
Publicado: (2022) -
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
por: Page, Brent D. G., et al.
Publicado: (2018) -
Hormone-control regions mediate steroid receptor–dependent genome organization
por: Le Dily, François, et al.
Publicado: (2019) -
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
por: Page, Brent D. G., et al.
Publicado: (2019)