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The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing
Oncogenic metadherin is a key contributor to tumourigenesis with metadherin expression and cytoplasmic localisation previously linked to poor survival. A number of reports have shown metadherin localises specifically to nuclear speckles known to be rich in RNA-binding proteins including the splicing...
Autores principales: | Luxton, Hayley J., Simpson, Benjamin S., Mills, Ian G., Brindle, Nicola R., Ahmed, Zeba, Stavrinides, Vasilis, Heavey, Susan, Stamm, Stefan, Whitaker, Hayley C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770463/ https://www.ncbi.nlm.nih.gov/pubmed/31450747 http://dx.doi.org/10.3390/cancers11091233 |
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