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Proximity ligation assay to study protein–protein interactions of proteins on two different cells

Protein–protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently developed method, the proximity ligation assay (PLA...

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Detalles Bibliográficos
Autores principales: Sable, Rushikesh, Jambunathan, Nithya, Singh, Sitanshu, Pallerla, Sandeep, Kousoulas, Konstantin G, Jois, Seetharama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770473/
https://www.ncbi.nlm.nih.gov/pubmed/30227746
http://dx.doi.org/10.2144/btn-2018-0049