Cargando…

Proximity ligation assay to study protein–protein interactions of proteins on two different cells

Protein–protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently developed method, the proximity ligation assay (PLA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sable, Rushikesh, Jambunathan, Nithya, Singh, Sitanshu, Pallerla, Sandeep, Kousoulas, Konstantin G, Jois, Seetharama
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Science Ltd 2018
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770473/ https://www.ncbi.nlm.nih.gov/pubmed/30227746 http://dx.doi.org/10.2144/btn-2018-0049

Ejemplares similares

Surfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI Inhibitors
por: Sable, Rushikesh, et al.
Publicado: (2015)

A peptidomimetic with a chiral switch is an inhibitor of epidermal growth factor receptor heterodimerization
por: Kanthala, Shanthi P., et al.
Publicado: (2017)

Predicted Structure and Functions of the Prototypic Alphaherpesvirus Herpes Simplex Virus Type-1 UL37 Tegument Protein
por: Collantes, Therese Marie A., et al.
Publicado: (2022)

Peptides, Peptidomimetics, and Polypeptides from Marine Sources: A Wealth of Natural Sources for Pharmaceutical Applications
por: Sable, Rushikesh, et al.
Publicado: (2017)

Targeting protein–protein interaction for immunomodulation: A sunflower trypsin inhibitor analog peptidomimetic suppresses RA progression in CIA model
por: Dahal, Achyut, et al.
Publicado: (2022)

Herpes Simplex Virus 1 UL37 Protein Tyrosine Residues Conserved among All Alphaherpesviruses Are Required for Interactions with Glycoprotein K, Cytoplasmic Virion Envelopment, and Infectious Virus Production
por: Chouljenko, Dmitry V., et al.
Publicado: (2016)

Cancer Vaccines, Treatment of the Future: With Emphasis on HER2-Positive Breast Cancer
por: Pallerla, Sandeep, et al.
Publicado: (2021)

In situ detection of protein-protein interaction by proximity ligation assay in patient derived brain tumor stem cells
por: Sharanek, Ahmad, et al.
Publicado: (2022)

Optimized proximity ligation assay (PLA) for detection of RNA-protein complex interactions in cell lines
por: George, Jasmine, et al.
Publicado: (2022)

Optimization of proximity ligation assay (PLA) for detection of protein interactions and fusion proteins in non-adherent cells: application to pre-B lymphocytes
por: Debaize, Lydie, et al.
Publicado: (2017)

Inactivation of the UL37 Deamidase Enhances Virus Replication and Spread of the HSV-1(VC2) Oncolytic Vaccine Strain and Secretion of GM-CSF
por: Clark, Carolyn M., et al.
Publicado: (2023)

Proximity ligation assays of protein and RNA interactions in the male-specific lethal complex on Drosophila melanogaster polytene chromosomes
por: Lindehell, Henrik, et al.
Publicado: (2015)

Two Sides to Every Story: Herpes Simplex Type-1 Viral Glycoproteins gB, gD, gH/gL, gK, and Cellular Receptors Function as Key Players in Membrane Fusion
por: Jambunathan, Nithya, et al.
Publicado: (2021)

In Situ Proximity Ligation Assays Indicate That Hemochromatosis Proteins Hfe and Transferrin Receptor 2 (Tfr2) Do Not Interact
por: Rishi, Gautam, et al.
Publicado: (2013)

Proximity Ligation In situ Assay is a Powerful Tool to Monitor Specific ATG Protein Interactions following Autophagy Induction
por: Gauthier, Thierry, et al.
Publicado: (2015)

Proximity Ligation Assay Detection of Protein–DNA Interactions—Is There a Link between Heme Oxygenase-1 and G-quadruplexes?
por: Krzeptowski, Wojciech, et al.
Publicado: (2021)

Quantifying RNA–protein interactions in situ using modified-MTRIPs and proximity ligation
por: Jung, Jeenah, et al.
Publicado: (2013)

Analysis of close associations of uropod-associated proteins in human T-cells using the proximity ligation assay
por: Baumann, Tommy, et al.
Publicado: (2013)

Detecting RNA-protein proximity at DNA double-strand breaks using combined fluorescence in situ hybridization with proximity ligation assay
por: Alagia, Adele, et al.
Publicado: (2023)

Proximity ligation assay to detect DUX4 protein in FSHD1 muscle: a pilot study
por: Beermann, Mary Lou, et al.
Publicado: (2022)

Detection, Visualization and Quantification of Protein Complexes in Human Alzheimer’s Disease Brains using Proximity Ligation Assay
por: Romero-Fernandez, Wilber, et al.
Publicado: (2023)

Detection, visualization and quantification of protein complexes in human Alzheimer’s disease brains using proximity ligation assay
por: Romero-Fernandez, Wilber, et al.
Publicado: (2023)

Lipidated Peptidomimetic Ligand-Functionalized HER2 Targeted Liposome as Nano-Carrier Designed for Doxorubicin Delivery in Cancer Therapy
por: Naik, Himgauri, et al.
Publicado: (2021)

In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons
por: Almandoz-Gil, Leire, et al.
Publicado: (2018)

Effects of Heat Shock Protein 90 Inhibition In the Lungs
por: Uddin, Mohammad A., et al.
Publicado: (2020)

Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays
por: Di Francesco, Laura, et al.
Publicado: (2018)

Association of the Protein-Tyrosine Phosphatase DEP-1 with Its Substrate FLT3 Visualized by In Situ Proximity Ligation Assay
por: Böhmer, Sylvia-Annette, et al.
Publicado: (2013)

Detecting G protein-coupled receptor complexes in postmortem human brain with proximity ligation assay and a Bayesian classifier
por: Zhu, Ying, et al.
Publicado: (2019)

Two protein/protein interaction assays in one go
por: Taipale, Mikko
Publicado: (2018)

Proximity assays for sensitive quantification of proteins
por: Greenwood, Christina, et al.
Publicado: (2015)

An antagonist of growth hormone-releasing hormone protects against LPS-induced increase of bronchoalveolar lavage fluid protein concentration
por: Akhter, Mohammad S., et al.
Publicado: (2022)

RNA Whole-Mount In situ Hybridisation Proximity Ligation Assay (rISH-PLA), an Assay for Detecting RNA-Protein Complexes in Intact Cells
por: Roussis, Ioannis M., et al.
Publicado: (2016)

In vivo studies of a peptidomimetic that targets EGFR dimerization in NSCLC
por: Shrestha, Leeza, et al.
Publicado: (2020)

Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition
por: Yao, Zhong, et al.
Publicado: (2020)

A new branched proximity hybridization assay for the quantification of nanoscale protein–protein proximity
por: Zheng, Shuangshuang, et al.
Publicado: (2019)

Identification of cytotoxic agents disrupting synovial sarcoma oncoprotein interactions by proximity ligation assay
por: Laporte, Aimée N., et al.
Publicado: (2016)

Protocol to assess RNA-RNA interactions in situ using an RNA-proximity ligation assay
por: Basavappa, Megha G., et al.
Publicado: (2022)

Profiling Cellular Protein Complexes by Proximity Ligation with Dual Tag Microarray Readout
por: Hammond, Maria, et al.
Publicado: (2012)

Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies
por: Zatloukal, Bernhard, et al.
Publicado: (2014)

Tyrosine phosphorylation profiling via in situ proximity ligation assay
por: Elfineh, Lioudmila, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_p7gof3j2gv7imhlr48frqli73f