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Insulin Receptor Isoform A Modulates Metabolic Reprogramming of Breast Cancer Cells in Response to IGF2 and Insulin Stimulation

Previously published work has demonstrated that overexpression of the insulin receptor isoform A (IR-A) might play a role in cancer progression and metastasis. The IR has a predominant metabolic role in physiology, but the potential role of IR-A in cancer metabolic reprogramming is unknown. We aimed...

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Detalles Bibliográficos
Autores principales: Vella, Veronica, Nicolosi, Maria Luisa, Giuliano, Marika, Morrione, Andrea, Malaguarnera, Roberta, Belfiore, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770491/
https://www.ncbi.nlm.nih.gov/pubmed/31480557
http://dx.doi.org/10.3390/cells8091017