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Insulin Receptor Isoform A Modulates Metabolic Reprogramming of Breast Cancer Cells in Response to IGF2 and Insulin Stimulation
Previously published work has demonstrated that overexpression of the insulin receptor isoform A (IR-A) might play a role in cancer progression and metastasis. The IR has a predominant metabolic role in physiology, but the potential role of IR-A in cancer metabolic reprogramming is unknown. We aimed...
Autores principales: | Vella, Veronica, Nicolosi, Maria Luisa, Giuliano, Marika, Morrione, Andrea, Malaguarnera, Roberta, Belfiore, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770491/ https://www.ncbi.nlm.nih.gov/pubmed/31480557 http://dx.doi.org/10.3390/cells8091017 |
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