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Creation of Cybrid Cultures Containing mtDNA Mutations m.12315G>A and m.1555G>A, Associated with Atherosclerosis

In the present work, a pilot creation of four cybrid cultures with high heteroplasmy level was performed using mitochondrial genome mutations m.12315G>A and m.1555G>A. According to data of our preliminary studies, the threshold heteroplasmy level of mutation m.12315G>A is associated with at...

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Detalles Bibliográficos
Autores principales: Sazonova, Margarita A., Sinyov, Vasily V., Ryzhkova, Anastasia I., Sazonova, Marina D., Khasanova, Zukhra B., Shkurat, Tatiana P., Karagodin, Vasily P., Orekhov, Alexander N., Sobenin, Igor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770504/
https://www.ncbi.nlm.nih.gov/pubmed/31540444
http://dx.doi.org/10.3390/biom9090499