DNA Damage Changes Distribution Pattern and Levels of HP1 Protein Isoforms in the Nucleolus and Increases Phosphorylation of HP1β-Ser88

The family of heterochromatin protein 1 (HP1) isoforms is essential for chromatin packaging, regulation of gene expression, and repair of damaged DNA. Here we document that γ-radiation reduced the number of HP1α-positive foci, but not HP1β and HP1γ foci, located in the vicinity of the fibrillarin-po...

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Detalles Bibliográficos
Autores principales: Legartová, Soňa, Lochmanová, Gabriela, Zdráhal, Zbyněk, Kozubek, Stanislav, Šponer, Jiří, Krepl, Miroslav, Pokorná, Pavlína, Bártová, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770535/
https://www.ncbi.nlm.nih.gov/pubmed/31533340
http://dx.doi.org/10.3390/cells8091097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770535/
https://www.ncbi.nlm.nih.gov/pubmed/31533340
http://dx.doi.org/10.3390/cells8091097

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