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2-Methoxy-7-Acetonyljuglone Isolated from Reynoutria japonica Increases the Activity of Nuclear Factor Erythroid 2-Related Factor-2 through Inhibition of Ubiquitin Degradation in HeLa Cells
The nuclear factor erythroid-derived 2-related factor 2 (NRF2) is a key transcription factor for the activation of genes responsible for oxidative stress and drug detoxification. Thus, it is important to identify NRF2 activators, which can be used to protect the cells from oxidative damage. Here, we...
Autores principales: | Kim, Jung-Hwan, Khalil, Atif Ali Khan, Kim, Hye-Jin, Kim, Sung-Eun, Ahn, Mi-Jeong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770542/ https://www.ncbi.nlm.nih.gov/pubmed/31540074 http://dx.doi.org/10.3390/antiox8090398 |
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