Cargando…

Down-Regulation of Phosphoribosyl Pyrophosphate Synthetase 1 Inhibits Neuroblastoma Cell Proliferation

Phosphoribosyl pyrophosphate synthetase 1 (PRPS1) is a key enzyme in de novo nucleotide synthesis and nucleotide salvage synthesis pathways that are critical for purine and pyrimidine biosynthesis. Abnormally high expression of PRPS1 can cause many diseases, including hearing loss, hypotonia, and at...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jifu, Ye, Junhong, Zhu, Shunqin, Cui, Hongjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770549/ https://www.ncbi.nlm.nih.gov/pubmed/31443513 http://dx.doi.org/10.3390/cells8090955

Ejemplares similares

Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase
por: Alderwick, Luke J, et al.
Publicado: (2011)

Pleiotropic role of Drosophila phosphoribosyl pyrophosphate synthetase in autophagy and lysosome homeostasis
por: Delos Santos, Keemo, et al.
Publicado: (2019)

Phosphoribosyl pyrophosphate synthetase activity affects growth and riboflavin production in Ashbya gossypii
por: Jiménez, Alberto, et al.
Publicado: (2008)

Retraction: Pleiotropic role of Drosophila phosphoribosyl pyrophosphate synthetase in autophagy and lysosome homeostasis
por: Santos, Keemo Delos, et al.
Publicado: (2022)

Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) depletion regulates spermatogenic cell apoptosis and is correlated with hypospermatogenesis
por: Lei, Bin, et al.
Publicado: (2019)

Phosphoribosyl pyrophosphate synthetases 2 knockdown inhibits prostate cancer progression by suppressing cell cycle and inducing cell apoptosis
por: Qiao, Hui, et al.
Publicado: (2020)

Clinical and genetic characteristics of a patient with phosphoribosyl pyrophosphate synthetase 1 deficiency and a systematic literature review
por: Štajer, Katarina, et al.
Publicado: (2023)

Down-regulation of CHERP inhibits neuroblastoma cell proliferation and induces apoptosis through ER stress induction
por: Zhang, Dunke, et al.
Publicado: (2017)

On-demand utilization of phosphoribosyl pyrophosphate by downstream anabolic pathways
por: Pinson, Benoît, et al.
Publicado: (2023)

Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase
por: Zhang, Fangliang, et al.
Publicado: (2015)

Phosphoribosyl Pyrophosphate Amido Transferase: A New Prognostic Biomarker for Hepatocellular Carcinoma
por: Chu, Qingfei, et al.
Publicado: (2022)

Overexpression of Phosphoribosyl Pyrophosphate Synthase Enhances Resistance of Chlamydomonas to Ionizing Radiation
por: Jung, Sera, et al.
Publicado: (2021)

Leflunomide Reduces Proliferation and Induces Apoptosis in Neuroblastoma Cells In Vitro and In Vivo
por: Zhu, Shunqin, et al.
Publicado: (2013)

Phosphoribosyl Pyrophosphate Amidotransferase Promotes the Progression of Thyroid Cancer via Regulating Pyruvate Kinase M2
por: Liu, Bing, et al.
Publicado: (2020)

Inhibition of H3K9 Methyltransferase G9a Repressed Cell Proliferation and Induced Autophagy in Neuroblastoma Cells
por: Ke, Xiao-Xue, et al.
Publicado: (2014)

Correction: Inhibition of H3K9 Methyltransferase G9a Repressed Cell Proliferation and Induced Autophagy in Neuroblastoma Cells
por: Ke, Xiao-Xue, et al.
Publicado: (2019)

Metabolic interaction between amino acid deprivation and cisplatin synergistically reduces phosphoribosyl-pyrophosphate and augments cisplatin cytotoxicity
por: Wahwah, Nisreen, et al.
Publicado: (2020)

Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
por: Chen, Peng, et al.
Publicado: (2015)

Role of several histone lysine methyltransferases in tumor development
por: LI, JIFU, et al.
Publicado: (2016)

Catalytic Cycle of the Bifunctional Enzyme Phosphoribosyl-ATP Pyrophosphohydrolase/Phosphoribosyl-AMP Cyclohydrolase
por: Fisher, Gemma, et al.
Publicado: (2023)

Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase
por: Gan, Ninghai, et al.
Publicado: (2019)

Triptolide inhibits cell proliferation and tumorigenicity of human neuroblastoma cells
por: YAN, XIAOMIN, et al.
Publicado: (2015)

TRIM59 knockdown inhibits cell proliferation by down-regulating the Wnt/β-catenin signaling pathway in neuroblastoma
por: Chen, Gang, et al.
Publicado: (2019)

Epigenetic regulation of NfatC1 transcription and osteoclastogenesis by nicotinamide phosphoribosyl transferase in the pathogenesis of arthritis
por: Li, Xuanan, et al.
Publicado: (2019)

Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB
por: Shin, Donghyuk, et al.
Publicado: (2020)

Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination
por: Kalayil, Sissy, et al.
Publicado: (2018)

Morusin inhibits cell proliferation and tumor growth by down-regulating c-Myc in human gastric cancer
por: Wang, Feng, et al.
Publicado: (2017)

The Silkworm Carboxypeptidase Inhibitor Prevents Gastric Cancer Cells’ Proliferation through the EGF/EGFR Signaling Pathway
por: Ye, Junhong, et al.
Publicado: (2023)

The Legionella Effector SdjA Is a Bifunctional Enzyme That Distinctly Regulates Phosphoribosyl Ubiquitination
por: Song, Lei, et al.
Publicado: (2021)

Essential role of GATA3 in regulation of differentiation and cell proliferation in SK-N-SH neuroblastoma cells
por: PENG, HONGWEI, et al.
Publicado: (2015)

TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway
por: Gu, Hongyu, et al.
Publicado: (2022)

Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway
por: Shi, Shaomin, et al.
Publicado: (2021)

The mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector
por: Akturk, Anil, et al.
Publicado: (2018)

A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination
por: Qiu, Jiazhang, et al.
Publicado: (2017)

Knockdown of arsenic resistance protein 2 inhibits human glioblastoma cell proliferation through the MAPK/ERK pathway
por: Ke, Xiao-Xue, et al.
Publicado: (2018)

Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down‐regulating CCNE2 in pancreatic ductal adenocarcinoma
por: Yang, Jie, et al.
Publicado: (2020)

Clinical implications of thymidylate synthetase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activity levels in colorectal carcinoma following radical resection and administration of adjuvant 5-FU chemotherapy
por: Ishikawa, Masashi, et al.
Publicado: (2008)

BMP4 and Neuregulin regulate the direction of mouse neural crest cell differentiation
por: Zhu, Shunqin, et al.
Publicado: (2019)

Corrigendum: Dihydrocapsaicin inhibits cell proliferation and metastasis in melanoma via down-regulating β-catenin pathway
por: Shi, Shaomin, et al.
Publicado: (2022)

A Bifunctional Enzyme of Legionella that Distinctly Regulates Phosphoribosyl Ubiquitination of the SidE Family Effectors
por: Jiao, Jun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_io6us13i3177vtjbs4eao3e4ij