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Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine

Over the last few decades, chitosan has become a good candidate for tissue engineering applications. Derived from chitin, chitosan is a unique natural polysaccharide with outstanding properties in line with excellent biodegradability, biocompatibility, and antimicrobial activity. Due to the presence...

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Autores principales: Sultankulov, Bolat, Berillo, Dmitriy, Sultankulova, Karina, Tokay, Tursonjan, Saparov, Arman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770583/
https://www.ncbi.nlm.nih.gov/pubmed/31509976
http://dx.doi.org/10.3390/biom9090470
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author Sultankulov, Bolat
Berillo, Dmitriy
Sultankulova, Karina
Tokay, Tursonjan
Saparov, Arman
author_facet Sultankulov, Bolat
Berillo, Dmitriy
Sultankulova, Karina
Tokay, Tursonjan
Saparov, Arman
author_sort Sultankulov, Bolat
collection PubMed
description Over the last few decades, chitosan has become a good candidate for tissue engineering applications. Derived from chitin, chitosan is a unique natural polysaccharide with outstanding properties in line with excellent biodegradability, biocompatibility, and antimicrobial activity. Due to the presence of free amine groups in its backbone chain, chitosan could be further chemically modified to possess additional functional properties useful for the development of different biomaterials in regenerative medicine. In the current review, we will highlight the progress made in the development of chitosan-containing bioscaffolds, such as gels, sponges, films, and fibers, and their possible applications in tissue repair and regeneration, as well as the use of chitosan as a component for drug delivery applications.
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spelling pubmed-67705832019-10-30 Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine Sultankulov, Bolat Berillo, Dmitriy Sultankulova, Karina Tokay, Tursonjan Saparov, Arman Biomolecules Review Over the last few decades, chitosan has become a good candidate for tissue engineering applications. Derived from chitin, chitosan is a unique natural polysaccharide with outstanding properties in line with excellent biodegradability, biocompatibility, and antimicrobial activity. Due to the presence of free amine groups in its backbone chain, chitosan could be further chemically modified to possess additional functional properties useful for the development of different biomaterials in regenerative medicine. In the current review, we will highlight the progress made in the development of chitosan-containing bioscaffolds, such as gels, sponges, films, and fibers, and their possible applications in tissue repair and regeneration, as well as the use of chitosan as a component for drug delivery applications. MDPI 2019-09-10 /pmc/articles/PMC6770583/ /pubmed/31509976 http://dx.doi.org/10.3390/biom9090470 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sultankulov, Bolat
Berillo, Dmitriy
Sultankulova, Karina
Tokay, Tursonjan
Saparov, Arman
Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine
title Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine
title_full Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine
title_fullStr Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine
title_full_unstemmed Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine
title_short Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine
title_sort progress in the development of chitosan-based biomaterials for tissue engineering and regenerative medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770583/
https://www.ncbi.nlm.nih.gov/pubmed/31509976
http://dx.doi.org/10.3390/biom9090470
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