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Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine
Over the last few decades, chitosan has become a good candidate for tissue engineering applications. Derived from chitin, chitosan is a unique natural polysaccharide with outstanding properties in line with excellent biodegradability, biocompatibility, and antimicrobial activity. Due to the presence...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770583/ https://www.ncbi.nlm.nih.gov/pubmed/31509976 http://dx.doi.org/10.3390/biom9090470 |
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author | Sultankulov, Bolat Berillo, Dmitriy Sultankulova, Karina Tokay, Tursonjan Saparov, Arman |
author_facet | Sultankulov, Bolat Berillo, Dmitriy Sultankulova, Karina Tokay, Tursonjan Saparov, Arman |
author_sort | Sultankulov, Bolat |
collection | PubMed |
description | Over the last few decades, chitosan has become a good candidate for tissue engineering applications. Derived from chitin, chitosan is a unique natural polysaccharide with outstanding properties in line with excellent biodegradability, biocompatibility, and antimicrobial activity. Due to the presence of free amine groups in its backbone chain, chitosan could be further chemically modified to possess additional functional properties useful for the development of different biomaterials in regenerative medicine. In the current review, we will highlight the progress made in the development of chitosan-containing bioscaffolds, such as gels, sponges, films, and fibers, and their possible applications in tissue repair and regeneration, as well as the use of chitosan as a component for drug delivery applications. |
format | Online Article Text |
id | pubmed-6770583 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-67705832019-10-30 Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine Sultankulov, Bolat Berillo, Dmitriy Sultankulova, Karina Tokay, Tursonjan Saparov, Arman Biomolecules Review Over the last few decades, chitosan has become a good candidate for tissue engineering applications. Derived from chitin, chitosan is a unique natural polysaccharide with outstanding properties in line with excellent biodegradability, biocompatibility, and antimicrobial activity. Due to the presence of free amine groups in its backbone chain, chitosan could be further chemically modified to possess additional functional properties useful for the development of different biomaterials in regenerative medicine. In the current review, we will highlight the progress made in the development of chitosan-containing bioscaffolds, such as gels, sponges, films, and fibers, and their possible applications in tissue repair and regeneration, as well as the use of chitosan as a component for drug delivery applications. MDPI 2019-09-10 /pmc/articles/PMC6770583/ /pubmed/31509976 http://dx.doi.org/10.3390/biom9090470 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sultankulov, Bolat Berillo, Dmitriy Sultankulova, Karina Tokay, Tursonjan Saparov, Arman Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine |
title | Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine |
title_full | Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine |
title_fullStr | Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine |
title_full_unstemmed | Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine |
title_short | Progress in the Development of Chitosan-Based Biomaterials for Tissue Engineering and Regenerative Medicine |
title_sort | progress in the development of chitosan-based biomaterials for tissue engineering and regenerative medicine |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770583/ https://www.ncbi.nlm.nih.gov/pubmed/31509976 http://dx.doi.org/10.3390/biom9090470 |
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