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Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor gene frequently found to be inactivated in over 30% of human cancers. PTEN encodes a 54-kDa lipid phosphatase that serves as a gatekeeper of the phosphoinositide 3-kinase pathway involved in the promotion of multipl...

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Detalles Bibliográficos
Autores principales: Liu, Tian, Wang, Yiwei, Wang, Yubing, Chan, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770588/
https://www.ncbi.nlm.nih.gov/pubmed/31454965
http://dx.doi.org/10.3390/cancers11091247