SIRT1-Dependent Upregulation of Antiglycative Defense in HUVECs Is Essential for Resveratrol Protection against High Glucose Stress

Uncontrolled accumulation of methylglyoxal (MG) and reactive oxygen species (ROS) occurs in hyperglycemia-induced endothelial dysfunction associated with diabetes. Resveratrol (RSV) protects the endothelium upon high glucose (HG); however, the mechanisms underlying such protective effects are still...

Descripción completa

Detalles Bibliográficos
Autores principales: Santini, Silvano Junior, Cordone, Valeria, Mijit, Mahmut, Bignotti, Virginio, Aimola, Pierpaolo, Dolo, Vincenza, Falone, Stefano, Amicarelli, Fernanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770647/
https://www.ncbi.nlm.nih.gov/pubmed/31480513
http://dx.doi.org/10.3390/antiox8090346

Ejemplares similares

Ejemplares similares