Production of IFNβ by Conventional Dendritic Cells after Stimulation with Viral Compounds and IFNβ-Independent IFNAR1-Signaling Pathways are Associated with Aggravation of Polymicrobial Sepsis

Viral infections are associated with increased incidence of severe sepsis. Particularly during the early stages, type I interferons (IFNs) are known mediators of detrimental effects. However, the functional role of early interferon β (IFNβ) and its cellular source during sepsis in the context of pre...

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Detalles Bibliográficos
Autores principales: Howe, Magdalena, Bauer, Jens, Schulze, Anja, Kropp, Sonja, Locksley, Richard M., Alferink, Judith, Weighardt, Heike, Scheu, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770674/
https://www.ncbi.nlm.nih.gov/pubmed/31500303
http://dx.doi.org/10.3390/ijms20184410

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