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Trends and Challenges in Tumor Anti-Angiogenic Therapies

Excessive abnormal angiogenesis plays a pivotal role in tumor progression and is a hallmark of solid tumors. This process is driven by an imbalance between pro- and anti-angiogenic factors dominated by the tissue hypoxia-triggered overproduction of vascular endothelial growth factor (VEGF). VEGF-med...

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Detalles Bibliográficos
Autores principales: Jászai, József, Schmidt, Mirko H.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770676/
https://www.ncbi.nlm.nih.gov/pubmed/31540455
http://dx.doi.org/10.3390/cells8091102