A Novel Chromosomal Translocation Identified due to Complex Genetic Instability in iPSC Generated for Choroideremia

Induced pluripotent stem cells (iPSCs) have revolutionized the study of human diseases as they can renew indefinitely, undergo multi-lineage differentiation, and generate disease-specific models. However, the difficulty of working with iPSCs is that they are prone to genetic instability. Furthermore...

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Detalles Bibliográficos
Autores principales: Erkilic, Nejla, Gatinois, Vincent, Torriano, Simona, Bouret, Pauline, Sanjurjo-Soriano, Carla, De Luca, Valerie, Damodar, Krishna, Cereso, Nicolas, Puechberty, Jacques, Sanchez-Alcudia, Rocio, Hamel, Christian P., Ayuso, Carmen, Meunier, Isabelle, Pellestor, Franck, Kalatzis, Vasiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770680/
https://www.ncbi.nlm.nih.gov/pubmed/31514470
http://dx.doi.org/10.3390/cells8091068

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