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Fisetin, a 3,7,3′,4′-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models

Psoriasis is a chronic immune-mediated skin disease that involves the interaction of immune and skin cells, and is characterized by cytokine-driven epidermal hyperplasia, deviant differentiation, inflammation, and angiogenesis. Because the available treatments for psoriasis have significant limitati...

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Detalles Bibliográficos
Autores principales: Chamcheu, Jean Christopher, Esnault, Stephane, Adhami, Vaqar M., Noll, Andrea L., Banang-Mbeumi, Sergette, Roy, Tithi, Singh, Sitanshu S., Huang, Shile, Kousoulas, Konstantin G., Mukhtar, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770767/
https://www.ncbi.nlm.nih.gov/pubmed/31540162
http://dx.doi.org/10.3390/cells8091089

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