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Does the Acknowledgement of αS1-Casein Genotype Affect the Estimation of Genetic Parameters and Prediction of Breeding Values for Milk Yield and Composition Quality-Related Traits in Murciano-Granadina?

SIMPLE SUMMARY: Genetic evaluations and the selection of breeding animals require the accurate estimation of genetic parameters for economically important traits. As a result, dairy livestock has evolved in response to the needs of producers and consumers. Genetic selection in goats has been mostly...

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Autores principales: Pizarro Inostroza, María Gabriela, Landi, Vincenzo, Navas González, Francisco Javier, León Jurado, Jose Manuel, Martínez Martínez, Amparo, Fernández Álvarez, Javier, Delgado Bermejo, Juan Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770805/
https://www.ncbi.nlm.nih.gov/pubmed/31540251
http://dx.doi.org/10.3390/ani9090679
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author Pizarro Inostroza, María Gabriela
Landi, Vincenzo
Navas González, Francisco Javier
León Jurado, Jose Manuel
Martínez Martínez, Amparo
Fernández Álvarez, Javier
Delgado Bermejo, Juan Vicente
author_facet Pizarro Inostroza, María Gabriela
Landi, Vincenzo
Navas González, Francisco Javier
León Jurado, Jose Manuel
Martínez Martínez, Amparo
Fernández Álvarez, Javier
Delgado Bermejo, Juan Vicente
author_sort Pizarro Inostroza, María Gabriela
collection PubMed
description SIMPLE SUMMARY: Genetic evaluations and the selection of breeding animals require the accurate estimation of genetic parameters for economically important traits. As a result, dairy livestock has evolved in response to the needs of producers and consumers. Genetic selection in goats has been mostly based on quantitative traits such as milk yield, fat, protein, and dry matter. However, as reported by the increased heritability values of these parameters after the inclusion of the different allelic variants of αS1 casein in evaluation models, the selection of animals carrying this gene could result in a more efficient genetic selection. High levels of genetic polymorphism (89.58% of polymorphic SNP—as only five out of the 48 SNPs assessed were monomorphic) that are related to greater production of coagulable proteins in milk, a fact that could be associated with a higher yield and improved curd firmness properties. ABSTRACT: A total of 2090 lactation records for 710 Murciano-Granadina goats were collected during the years 2005–2016 and analyzed to investigate the influence of the αS1-CN genotype on milk yield and components (protein, fat, and dry matter). Goats were genetically evaluated, including and excluding the αS1-CN genotype, in order to assess its repercussion on the efficiency of breeding models. Despite no significant differences being found for milk yield, fat and dry matter heritabilities, protein production heritability considerably increased after aS1-CN genotype was included in the breeding model (+0.23). Standard errors suggest that the consideration of genotype may improve the model’s efficiency, translating into more accurate genetic parameters and breeding values (PBV). Genetic correlations ranged from −0.15 to −0.01 between protein/dry matter and milk yield/protein and fat content, while phenotypic correlations were −0.02 for milk/protein and −0.01 for milk/fat or protein content. For males, the broadest range for reliability (R(AP)) (0.45–0.71) was similar to that of females (0.37–0.86) when the genotype was included. PBV ranges broadened while the maximum remained similar (0.61–0.77) for males and females (0.62–0.81) when the genotype was excluded, respectively. Including the αS1-CN genotype can increase production efficiency, milk profitability, milk yield, fat, protein and dry matter contents in Murciano-Granadina dairy breeding programs.
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spelling pubmed-67708052019-10-30 Does the Acknowledgement of αS1-Casein Genotype Affect the Estimation of Genetic Parameters and Prediction of Breeding Values for Milk Yield and Composition Quality-Related Traits in Murciano-Granadina? Pizarro Inostroza, María Gabriela Landi, Vincenzo Navas González, Francisco Javier León Jurado, Jose Manuel Martínez Martínez, Amparo Fernández Álvarez, Javier Delgado Bermejo, Juan Vicente Animals (Basel) Article SIMPLE SUMMARY: Genetic evaluations and the selection of breeding animals require the accurate estimation of genetic parameters for economically important traits. As a result, dairy livestock has evolved in response to the needs of producers and consumers. Genetic selection in goats has been mostly based on quantitative traits such as milk yield, fat, protein, and dry matter. However, as reported by the increased heritability values of these parameters after the inclusion of the different allelic variants of αS1 casein in evaluation models, the selection of animals carrying this gene could result in a more efficient genetic selection. High levels of genetic polymorphism (89.58% of polymorphic SNP—as only five out of the 48 SNPs assessed were monomorphic) that are related to greater production of coagulable proteins in milk, a fact that could be associated with a higher yield and improved curd firmness properties. ABSTRACT: A total of 2090 lactation records for 710 Murciano-Granadina goats were collected during the years 2005–2016 and analyzed to investigate the influence of the αS1-CN genotype on milk yield and components (protein, fat, and dry matter). Goats were genetically evaluated, including and excluding the αS1-CN genotype, in order to assess its repercussion on the efficiency of breeding models. Despite no significant differences being found for milk yield, fat and dry matter heritabilities, protein production heritability considerably increased after aS1-CN genotype was included in the breeding model (+0.23). Standard errors suggest that the consideration of genotype may improve the model’s efficiency, translating into more accurate genetic parameters and breeding values (PBV). Genetic correlations ranged from −0.15 to −0.01 between protein/dry matter and milk yield/protein and fat content, while phenotypic correlations were −0.02 for milk/protein and −0.01 for milk/fat or protein content. For males, the broadest range for reliability (R(AP)) (0.45–0.71) was similar to that of females (0.37–0.86) when the genotype was included. PBV ranges broadened while the maximum remained similar (0.61–0.77) for males and females (0.62–0.81) when the genotype was excluded, respectively. Including the αS1-CN genotype can increase production efficiency, milk profitability, milk yield, fat, protein and dry matter contents in Murciano-Granadina dairy breeding programs. MDPI 2019-09-13 /pmc/articles/PMC6770805/ /pubmed/31540251 http://dx.doi.org/10.3390/ani9090679 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pizarro Inostroza, María Gabriela
Landi, Vincenzo
Navas González, Francisco Javier
León Jurado, Jose Manuel
Martínez Martínez, Amparo
Fernández Álvarez, Javier
Delgado Bermejo, Juan Vicente
Does the Acknowledgement of αS1-Casein Genotype Affect the Estimation of Genetic Parameters and Prediction of Breeding Values for Milk Yield and Composition Quality-Related Traits in Murciano-Granadina?
title Does the Acknowledgement of αS1-Casein Genotype Affect the Estimation of Genetic Parameters and Prediction of Breeding Values for Milk Yield and Composition Quality-Related Traits in Murciano-Granadina?
title_full Does the Acknowledgement of αS1-Casein Genotype Affect the Estimation of Genetic Parameters and Prediction of Breeding Values for Milk Yield and Composition Quality-Related Traits in Murciano-Granadina?
title_fullStr Does the Acknowledgement of αS1-Casein Genotype Affect the Estimation of Genetic Parameters and Prediction of Breeding Values for Milk Yield and Composition Quality-Related Traits in Murciano-Granadina?
title_full_unstemmed Does the Acknowledgement of αS1-Casein Genotype Affect the Estimation of Genetic Parameters and Prediction of Breeding Values for Milk Yield and Composition Quality-Related Traits in Murciano-Granadina?
title_short Does the Acknowledgement of αS1-Casein Genotype Affect the Estimation of Genetic Parameters and Prediction of Breeding Values for Milk Yield and Composition Quality-Related Traits in Murciano-Granadina?
title_sort does the acknowledgement of αs1-casein genotype affect the estimation of genetic parameters and prediction of breeding values for milk yield and composition quality-related traits in murciano-granadina?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770805/
https://www.ncbi.nlm.nih.gov/pubmed/31540251
http://dx.doi.org/10.3390/ani9090679
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