The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer’s Disease and Parkinson’s Disease and Models of Mild Cognitive Impairment

Many neurodegenerative disorders have lysosomal impediments, and the list of proposed treatments targeting lysosomes is growing. We investigated the role of lysosomes in Alzheimer’s disease (AD) and other age-related disorders, as well as in a strategy to compensate for lysosomal disturbances. Compr...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Jeannie, Estick, Candice M., Ikonne, Uzoma S., Butler, David, Pait, Morgan C., Elliott, Lyndsie H., Ruiz, Sarah, Smith, Kaitlan, Rentschler, Katherine M., Mundell, Cary, Almeida, Michael F., Bear, Nicole Stumbling, Locklear, James P., Abumohsen, Yara, Ivey, Cecily M., Farizatto, Karen L.G., Bahr, Ben A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770842/
https://www.ncbi.nlm.nih.gov/pubmed/31505809
http://dx.doi.org/10.3390/ijms20184432

Ejemplares similares

Ejemplares similares