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Hepatic Transcriptomics Reveals that Lipogenesis Is a Key Signaling Pathway in Isocitrate Dehydrogenase 2 Deficient Mice
Mitochondrial nicotinamide adenine dinucleotide phosphate (NADP(+))-dependent isocitrate dehydrogenase (IDH2) plays a key role in the intermediary metabolism and energy production via catalysing oxidative decarboxylation of isocitrate to α-ketoglutarate in the tricarboxylic acid (TCA) cycle. Despite...
Autores principales: | Pan, Jeong Hoon, Tang, Jingsi, Redding, Mersady C., Beane, Kaleigh E., Conner, Cara L., Cho, Yun Jeong, Zhao, Jiangchao, Kim, Jun Ho, Kong, Byungwhi C., Lee, Jin Hyup, Kim, Jae Kyeom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770969/ https://www.ncbi.nlm.nih.gov/pubmed/31546946 http://dx.doi.org/10.3390/genes10090728 |
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