Optical Diagnostic Based on Functionalized Gold Nanoparticles

Au nanoparticles (NPs) possess unique physicochemical and optical properties, showing great potential in biomedical applications. Diagnostic spectroscopy utilizing varied Au NPs has become a precision tool of in vitro and in vivo diagnostic for cancer and other specific diseases. In this review, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Ou, Jiemei, Zhou, Zidan, Chen, Zhong, Tan, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770972/
https://www.ncbi.nlm.nih.gov/pubmed/31491861
http://dx.doi.org/10.3390/ijms20184346
_version_ 1783455608779833344
author Ou, Jiemei
Zhou, Zidan
Chen, Zhong
Tan, Huijun
author_facet Ou, Jiemei
Zhou, Zidan
Chen, Zhong
Tan, Huijun
author_sort Ou, Jiemei
collection PubMed
description Au nanoparticles (NPs) possess unique physicochemical and optical properties, showing great potential in biomedical applications. Diagnostic spectroscopy utilizing varied Au NPs has become a precision tool of in vitro and in vivo diagnostic for cancer and other specific diseases. In this review, we tried to comprehensively introduce the remarkable optical properties of Au NPs, including localized surfaces plasmon resonance (LSPR), surface-enhanced Raman scattering (SERS), and metal-enhanced fluorescence (MEF). Then, we highlighted the excellent works using Au NPs for optical diagnostic applications. Ultimately, the challenges and future perspective of using Au NPs for optical diagnostic were discussed.
format Online
Article
Text
id pubmed-6770972
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-67709722019-10-30 Optical Diagnostic Based on Functionalized Gold Nanoparticles Ou, Jiemei Zhou, Zidan Chen, Zhong Tan, Huijun Int J Mol Sci Review Au nanoparticles (NPs) possess unique physicochemical and optical properties, showing great potential in biomedical applications. Diagnostic spectroscopy utilizing varied Au NPs has become a precision tool of in vitro and in vivo diagnostic for cancer and other specific diseases. In this review, we tried to comprehensively introduce the remarkable optical properties of Au NPs, including localized surfaces plasmon resonance (LSPR), surface-enhanced Raman scattering (SERS), and metal-enhanced fluorescence (MEF). Then, we highlighted the excellent works using Au NPs for optical diagnostic applications. Ultimately, the challenges and future perspective of using Au NPs for optical diagnostic were discussed. MDPI 2019-09-05 /pmc/articles/PMC6770972/ /pubmed/31491861 http://dx.doi.org/10.3390/ijms20184346 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ou, Jiemei
Zhou, Zidan
Chen, Zhong
Tan, Huijun
Optical Diagnostic Based on Functionalized Gold Nanoparticles
title Optical Diagnostic Based on Functionalized Gold Nanoparticles
title_full Optical Diagnostic Based on Functionalized Gold Nanoparticles
title_fullStr Optical Diagnostic Based on Functionalized Gold Nanoparticles
title_full_unstemmed Optical Diagnostic Based on Functionalized Gold Nanoparticles
title_short Optical Diagnostic Based on Functionalized Gold Nanoparticles
title_sort optical diagnostic based on functionalized gold nanoparticles
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770972/
https://www.ncbi.nlm.nih.gov/pubmed/31491861
http://dx.doi.org/10.3390/ijms20184346
work_keys_str_mv AT oujiemei opticaldiagnosticbasedonfunctionalizedgoldnanoparticles
AT zhouzidan opticaldiagnosticbasedonfunctionalizedgoldnanoparticles
AT chenzhong opticaldiagnosticbasedonfunctionalizedgoldnanoparticles
AT tanhuijun opticaldiagnosticbasedonfunctionalizedgoldnanoparticles

Ejemplares similares