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Focal Recurrent Copy Number Alterations Characterize Disease Relapse in High Grade Serous Ovarian Cancer Patients with Good Clinical Prognosis: A Pilot Study
High grade serous ovarian cancer (HGSOC) retains high molecular heterogeneity and genomic instability, which currently limit the treatment opportunities. HGSOC patients receiving complete cytoreduction (R0) at primary surgery and platinum-based therapy may unevenly experience early disease relapse,...
Autores principales: | Dugo, Matteo, Devecchi, Andrea, De Cecco, Loris, Cecchin, Erika, Mezzanzanica, Delia, Sensi, Marialuisa, Bagnoli, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770978/ https://www.ncbi.nlm.nih.gov/pubmed/31491988 http://dx.doi.org/10.3390/genes10090678 |
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