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Selecting short length nucleic acids localized in exosomes improves plasma EGFR mutation detection in NSCLC patients
BACKGROUND: Exosomal nucleic acid (exoNA) is a feasible target to improve the sensitivity of EGFR mutation testing in non-small cell lung cancer patients with limited cell-free DNA (cfDNA) mutant copies. However, the type and size of target exoNA related to the sensitivity of EGFR mutation testing h...
Autores principales: | Kim, Yoonjung, Shin, Saeam, Kim, Boyeon, Lee, Kyung-A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771088/ https://www.ncbi.nlm.nih.gov/pubmed/31582907 http://dx.doi.org/10.1186/s12935-019-0978-8 |
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