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Selecting short length nucleic acids localized in exosomes improves plasma EGFR mutation detection in NSCLC patients

BACKGROUND: Exosomal nucleic acid (exoNA) is a feasible target to improve the sensitivity of EGFR mutation testing in non-small cell lung cancer patients with limited cell-free DNA (cfDNA) mutant copies. However, the type and size of target exoNA related to the sensitivity of EGFR mutation testing h...

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Detalles Bibliográficos
Autores principales: Kim, Yoonjung, Shin, Saeam, Kim, Boyeon, Lee, Kyung-A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771088/
https://www.ncbi.nlm.nih.gov/pubmed/31582907
http://dx.doi.org/10.1186/s12935-019-0978-8

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