Metformin paradoxically worsens insulin resistance in SHORT syndrome

BACKGROUND: SHORT syndrome is an autosomal dominant condition associated severe insulin resistance (IR) and lipoatrophy due to post-receptor defect in insulin signaling involving phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1), where no clear treatment guidelines are available. METHODS: We a...

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Detalles Bibliográficos
Autores principales: Lewandowski, Krzysztof C., Dąbrowska, Katarzyna, Brzozowska, Maria, Kawalec, Joanna, Lewiński, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771105/
https://www.ncbi.nlm.nih.gov/pubmed/31583022
http://dx.doi.org/10.1186/s13098-019-0477-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771105/
https://www.ncbi.nlm.nih.gov/pubmed/31583022
http://dx.doi.org/10.1186/s13098-019-0477-z

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