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Metformin paradoxically worsens insulin resistance in SHORT syndrome
BACKGROUND: SHORT syndrome is an autosomal dominant condition associated severe insulin resistance (IR) and lipoatrophy due to post-receptor defect in insulin signaling involving phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1), where no clear treatment guidelines are available. METHODS: We a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771105/ https://www.ncbi.nlm.nih.gov/pubmed/31583022 http://dx.doi.org/10.1186/s13098-019-0477-z |