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Liver‐Targeted Toll‐Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus

Current therapeutics for chronic infection with hepatitis B virus (HBV) rarely induce functional cure due to the immunotolerant status of patients. Small molecule agonists targeting toll‐like receptor 7 (TLR7) have been shown to elicit a functional cure in animal models of HBV but sometimes with poo...

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Detalles Bibliográficos
Autores principales: Korolowizc, Kyle E., Li, Bin, Huang, Xu, Yon, Changsuek, Rodrigo, Evelyn, Corpuz, Manny, Plouffe, David M., Kallakury, Bhaskar V., Suresh, Manasa, Wu, Tom Y.‐H., Miller, Andrew T., Menne, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771164/
https://www.ncbi.nlm.nih.gov/pubmed/31592075
http://dx.doi.org/10.1002/hep4.1397