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Liver‐Targeted Toll‐Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus
Current therapeutics for chronic infection with hepatitis B virus (HBV) rarely induce functional cure due to the immunotolerant status of patients. Small molecule agonists targeting toll‐like receptor 7 (TLR7) have been shown to elicit a functional cure in animal models of HBV but sometimes with poo...
Autores principales: | Korolowizc, Kyle E., Li, Bin, Huang, Xu, Yon, Changsuek, Rodrigo, Evelyn, Corpuz, Manny, Plouffe, David M., Kallakury, Bhaskar V., Suresh, Manasa, Wu, Tom Y.‐H., Miller, Andrew T., Menne, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771164/ https://www.ncbi.nlm.nih.gov/pubmed/31592075 http://dx.doi.org/10.1002/hep4.1397 |
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