FDG PET/CT with SPM Analysis in Early Diagnosis of Clinically Suspected Osmotic Demyelination Syndrome with Non-contributory MRI

Early diagnosis is imperative for adequate management of patients with osmotic demyelination syndrome (ODS), which is usually a result of rapid shifts of osmolality secondary to rapid correction of hyponatremia. Magnetic resonance imaging (MRI) with its special sequences is the investigation of choi...

Descripción completa

Detalles Bibliográficos
Autores principales: Seniaray, Nikhil, Verma, Ritu, Ranjan, Rajeev, Belho, Ethel, Malik, Dharmender, Gupta, Vanshika, Jaimini, Abhinav, Mahajan, Harsh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771194/
https://www.ncbi.nlm.nih.gov/pubmed/31579357
http://dx.doi.org/10.4103/ijnm.IJNM_95_19
_version_ 1783455646588338176
author Seniaray, Nikhil
Verma, Ritu
Ranjan, Rajeev
Belho, Ethel
Malik, Dharmender
Gupta, Vanshika
Jaimini, Abhinav
Mahajan, Harsh
author_facet Seniaray, Nikhil
Verma, Ritu
Ranjan, Rajeev
Belho, Ethel
Malik, Dharmender
Gupta, Vanshika
Jaimini, Abhinav
Mahajan, Harsh
author_sort Seniaray, Nikhil
collection PubMed
description Early diagnosis is imperative for adequate management of patients with osmotic demyelination syndrome (ODS), which is usually a result of rapid shifts of osmolality secondary to rapid correction of hyponatremia. Magnetic resonance imaging (MRI) with its special sequences is the investigation of choice for early detection of the osmotic changes in the brain. We report a case of clinically suspected ODS with noncontributory MRI and positive fluoro-2-deoxy-d-glucose positron emission tomography (FDG PET) scan with statistical parametric mapping (SPM) analysis, which localized the focal hypermetabolism in the basal ganglia, thalamus, pons, and cerebellum.
format Online
Article
Text
id pubmed-6771194
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-67711942019-10-02 FDG PET/CT with SPM Analysis in Early Diagnosis of Clinically Suspected Osmotic Demyelination Syndrome with Non-contributory MRI Seniaray, Nikhil Verma, Ritu Ranjan, Rajeev Belho, Ethel Malik, Dharmender Gupta, Vanshika Jaimini, Abhinav Mahajan, Harsh Indian J Nucl Med Interesting Image Early diagnosis is imperative for adequate management of patients with osmotic demyelination syndrome (ODS), which is usually a result of rapid shifts of osmolality secondary to rapid correction of hyponatremia. Magnetic resonance imaging (MRI) with its special sequences is the investigation of choice for early detection of the osmotic changes in the brain. We report a case of clinically suspected ODS with noncontributory MRI and positive fluoro-2-deoxy-d-glucose positron emission tomography (FDG PET) scan with statistical parametric mapping (SPM) analysis, which localized the focal hypermetabolism in the basal ganglia, thalamus, pons, and cerebellum. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6771194/ /pubmed/31579357 http://dx.doi.org/10.4103/ijnm.IJNM_95_19 Text en Copyright: © 2019 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Seniaray, Nikhil
Verma, Ritu
Ranjan, Rajeev
Belho, Ethel
Malik, Dharmender
Gupta, Vanshika
Jaimini, Abhinav
Mahajan, Harsh
FDG PET/CT with SPM Analysis in Early Diagnosis of Clinically Suspected Osmotic Demyelination Syndrome with Non-contributory MRI
title FDG PET/CT with SPM Analysis in Early Diagnosis of Clinically Suspected Osmotic Demyelination Syndrome with Non-contributory MRI
title_full FDG PET/CT with SPM Analysis in Early Diagnosis of Clinically Suspected Osmotic Demyelination Syndrome with Non-contributory MRI
title_fullStr FDG PET/CT with SPM Analysis in Early Diagnosis of Clinically Suspected Osmotic Demyelination Syndrome with Non-contributory MRI
title_full_unstemmed FDG PET/CT with SPM Analysis in Early Diagnosis of Clinically Suspected Osmotic Demyelination Syndrome with Non-contributory MRI
title_short FDG PET/CT with SPM Analysis in Early Diagnosis of Clinically Suspected Osmotic Demyelination Syndrome with Non-contributory MRI
title_sort fdg pet/ct with spm analysis in early diagnosis of clinically suspected osmotic demyelination syndrome with non-contributory mri
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771194/
https://www.ncbi.nlm.nih.gov/pubmed/31579357
http://dx.doi.org/10.4103/ijnm.IJNM_95_19
work_keys_str_mv AT seniaraynikhil fdgpetctwithspmanalysisinearlydiagnosisofclinicallysuspectedosmoticdemyelinationsyndromewithnoncontributorymri
AT vermaritu fdgpetctwithspmanalysisinearlydiagnosisofclinicallysuspectedosmoticdemyelinationsyndromewithnoncontributorymri
AT ranjanrajeev fdgpetctwithspmanalysisinearlydiagnosisofclinicallysuspectedosmoticdemyelinationsyndromewithnoncontributorymri
AT belhoethel fdgpetctwithspmanalysisinearlydiagnosisofclinicallysuspectedosmoticdemyelinationsyndromewithnoncontributorymri
AT malikdharmender fdgpetctwithspmanalysisinearlydiagnosisofclinicallysuspectedosmoticdemyelinationsyndromewithnoncontributorymri
AT guptavanshika fdgpetctwithspmanalysisinearlydiagnosisofclinicallysuspectedosmoticdemyelinationsyndromewithnoncontributorymri
AT jaiminiabhinav fdgpetctwithspmanalysisinearlydiagnosisofclinicallysuspectedosmoticdemyelinationsyndromewithnoncontributorymri
AT mahajanharsh fdgpetctwithspmanalysisinearlydiagnosisofclinicallysuspectedosmoticdemyelinationsyndromewithnoncontributorymri

Ejemplares similares